The CrySiV

Crystallization Simulation and Visualization tool

A population balance model based crystallization process simulator for cooling, antisolvent and combined cooling and antisolvent crystallization.

Accurate numerics

CrySiV implements a high resolution finite volume method (HR-FVM) on non-uniform grids for numerical solutions, which ensures the accuracy. The solvers are coded in C and CUDA C languages for improved CPU time. CrySiV implements the HR-FVM for both 1D and 2D PBEs.

Efficient
HR-FVM

Crystallization mechanisms

CrySiV implements all the common crystallization mechanisms, including the primary and secondary nucleation of crystals, crystal growth and dissolution as well as agglomeration and breakage. The users can select and configure predefined rate equations. 

All major
mechanisms

Parameter estimations

Having access to accurate kinetic parameters is paramount for model based design. CrySiV has an advanced parameter estimation tool, which enables to regress the kinetic parameters based on the experimental data, using high performance optimization methods.  

Global
optimization

Demo videos

Experimental data input tool: tailored to your PAT tools and minimizes your pre-formatting efforts
Parameter estimation module: a powerful tool to fit the model quickly and interactively
Simulations tool: use your illusion, run various batch, semi-batch and continuous simulations
Visualizations tool: compare your simulations. Create images and animated .gifs

Downloads

Download a demo CrySiV version for evaluation. You will be able to input only one experiment in the experimental data input tool. There are no other limitations .
Download the CrySiV documentation, step-by-step training materials and the corresponding supporting files.